Emergency crews were called to the scene at Oak Shade Cheese factory in Kirkwood, Little Britain Township around 3 p.m., dispatchers at LCWC detailed.
Although smoke with the only thing reported, more than 20 fire crews responded to the scene.
At least one building was evacuated, according to dispatchers.
No injuries have been reported. A tanker crew remained on the scene as of 5 p.m.
The 220 block of Reath Road was closed at the time of reporting.
Check back here for possible updates.
Click here to follow Daily Voice Middletown-Lower Swatara and receive free news updates.